Abstract: Resources are the foundation of mineral development, and the morphology and spatial distribution of ore bodies are crucial for mine exploitation design. In geologically complex mining areas, exploration is constrained by factors such as investment costs, return on investment, green exploration requirements, and environmental protection standards, leading to limitations in exploration methods and engineering network density. The resulting geological information is limited, causing discrepancies between theoretical understanding of metallogenic patterns and reality. Consequently, the established ore body models and their spatial distribution may deviate from actual conditions, impacting resource extraction and utilization. To enhance the service and guidance of three-dimensional geological models and mining geological work for resource development, a polymetallic mine in Yunnan is taken as a case. It investigates the metallogenic patterns and the optimization of three-dimensional geological models, applying these findings to support and guide production. The research highlights the significance of these findings for resource development. Through this study, a workflow and methodology for metallogenic patterns — three-dimensional geological model establishment (optimization) — application in production are summarized: metallogenic patterns — three-dimensional geological model establishment (optimization) — application in resource development — continuous metallogenic research during resource extraction — ongoing (optimized) three-dimensional geological model development — continuous application in production. The research outcomes represent a successful integration of metallogenic pattern studies, three-dimensional geological modeling, and production, serving as a typical example of the deep integration of industry, academia, research, and application, with notable potential for broader implementation.